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Investigating Derivatives of Tanshinone IIA Sulfonate Sodium and Chloroxine for Their Inhibition Activities against the SARS-CoV-2 Papain-like Protease

[Image: see text] SARS-CoV-2 has caused a global pandemic of COVID-19, posing a huge threat to public health. The SARS-CoV-2 papain-like cysteine protease (PLpro) plays a significant role in virus replication and host immune regulation, which is a promising antiviral drug target. Several potential i...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Chen, Ke, Zhang, Zhaoyong, Wei, Peilan, Zhang, Lu, Xu, Yunxia, Lun, Qili, Ma, Yanhong, Wu, Fang, Zhang, Ying, Wang, Yanqun, Zhao, Jincun, Zhou, Yaoqi, Zhan, Jian, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798770/
https://www.ncbi.nlm.nih.gov/pubmed/36591160
http://dx.doi.org/10.1021/acsomega.2c06675