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Stability of Phenyl-Modified Triphenylphosphonium Conjugates and Interactions with DTPA

[Image: see text] Triphenylphosphonium (TPP(+)) conjugates are effective in targeting drugs and probes to the mitochondria due to their lipophilic character that allows them to readily cross membranes and their large cationic radius that enables mitochondrial uptake because of the mitochondria’s neg...

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Detalles Bibliográficos
Autores principales: Gruenwald, Hannah K., Kerns, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798776/
https://www.ncbi.nlm.nih.gov/pubmed/36591157
http://dx.doi.org/10.1021/acsomega.2c06525