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PVECs‐Derived Exosomal microRNAs Regulate PASMCs via FoxM1 Signaling in IUGR‐induced Pulmonary Hypertension

BACKGROUND: Intrauterine growth restriction (IUGR) is closely related to systemic or pulmonary hypertension (PH) in adulthood. Aberrant crosstalk between pulmonary vascular endothelial cells (PVECs) and pulmonary arterial smooth muscle cells (PASMCs) that is mediated by exosomes plays an essential r...

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Detalles Bibliográficos
Autores principales: Luo, Xiaofei, Hang, Chengcheng, Zhang, Ziming, Le, Kaixing, Ying, Yuhan, Lv, Ying, Yan, Lingling, Huang, Yajie, Ye, Lixia, Xu, Xuefeng, Zhong, Ying, Du, Lizhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798821/
https://www.ncbi.nlm.nih.gov/pubmed/36533591
http://dx.doi.org/10.1161/JAHA.122.027177