Two-Stage SN38 Release from a Core–Shell Nanoparticle Enhances Tumor Deposition and Antitumor Efficacy for Synergistic Combination with Immune Checkpoint Blockade

[Image: see text] Long-circulating nanomedicines efficiently deliver chemotherapies to tumors to reduce general toxicity. However, extended blood circulation of nanomedicines can increase drug exposure to leukocytes and lead to hematological toxicity. Here, we report a two-stage release strategy to...

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Detalles Bibliográficos
Autores principales: Jiang, Xiaomin, Lee, Morten, Xia, Junjie, Luo, Taokun, Liu, Jianqiao, Rodriguez, Megan, Lin, Wenbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798857/
https://www.ncbi.nlm.nih.gov/pubmed/36382721
http://dx.doi.org/10.1021/acsnano.2c09788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798857/
https://www.ncbi.nlm.nih.gov/pubmed/36382721
http://dx.doi.org/10.1021/acsnano.2c09788

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