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Integration of In Vitro and In Vivo Models to Predict Cellular and Tissue Dosimetry of Nanomaterials Using Physiologically Based Pharmacokinetic Modeling

[Image: see text] Nanomaterials (NMs) have been increasingly used in a number of areas, including consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation of safety, efficacy, and potential toxicity of NMs. Current evaluation of NM efficacy and safety involves the t...

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Detalles Bibliográficos
Autores principales: Lin, Zhoumeng, Aryal, Santosh, Cheng, Yi-Hsien, Gesquiere, Andre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798869/
https://www.ncbi.nlm.nih.gov/pubmed/36520546
http://dx.doi.org/10.1021/acsnano.2c07312