Polycarcin V induces DNA-damage response and enables the profiling of DNA-binding proteins

To maintain genomic integrity and avoid diseases, the DNA-damage response (DDR) not only detects and repairs DNA lesions, but also contributes to the resistance to DNA-damaging chemotherapeutics. Targeting the DDR plays a significant role in drug discovery using the principle of synthetic lethality....

Descripción completa

Detalles Bibliográficos
Autores principales: Yue, Zongwei, Wu, Fan, Guo, Fusheng, Park, Jiyeong, Wang, Jin, Zhang, Liyun, Liao, Daohong, Li, Wenyang, Schärer, Orlando D, Lei, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
RESEARCH ARTICLE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798893/
https://www.ncbi.nlm.nih.gov/pubmed/36601137
http://dx.doi.org/10.1093/nsr/nwac046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798893/
https://www.ncbi.nlm.nih.gov/pubmed/36601137
http://dx.doi.org/10.1093/nsr/nwac046

Ejemplares similares