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Polycarcin V induces DNA-damage response and enables the profiling of DNA-binding proteins

To maintain genomic integrity and avoid diseases, the DNA-damage response (DDR) not only detects and repairs DNA lesions, but also contributes to the resistance to DNA-damaging chemotherapeutics. Targeting the DDR plays a significant role in drug discovery using the principle of synthetic lethality....

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Detalles Bibliográficos
Autores principales:	Yue, Zongwei, Wu, Fan, Guo, Fusheng, Park, Jiyeong, Wang, Jin, Zhang, Liyun, Liao, Daohong, Li, Wenyang, Schärer, Orlando D, Lei, Xiaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	RESEARCH ARTICLE
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9798893/ https://www.ncbi.nlm.nih.gov/pubmed/36601137 http://dx.doi.org/10.1093/nsr/nwac046

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