Targeting RUNX1 as a novel treatment modality for pulmonary arterial hypertension

AIMS: Pulmonary arterial hypertension (PAH) is a fatal disease without a cure. Previously, we found that transcription factor RUNX1-dependent haematopoietic transformation of endothelial progenitor cells may contribute to the pathogenesis of PAH. However, the therapeutic potential of RUNX1 inhibitio...

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Detalles Bibliográficos
Autores principales: Jeong, Euy-Myoung, Pereira, Mandy, So, Eui-Young, Wu, Keith Q, Del Tatto, Michael, Wen, Sicheng, Dooner, Mark S, Dubielecka, Patrycja M, Reginato, Anthony M, Ventetuolo, Corey E, Quesenberry, Peter J, Klinger, James R, Liang, Olin D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799056/
https://www.ncbi.nlm.nih.gov/pubmed/35018410
http://dx.doi.org/10.1093/cvr/cvac001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799056/
https://www.ncbi.nlm.nih.gov/pubmed/35018410
http://dx.doi.org/10.1093/cvr/cvac001

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