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Bridging the In Vitro to In Vivo gap: Using the Chick Embryo Model to Accelerate Nanoparticle Validation and Qualification for In Vivo studies

[Image: see text] We postulate that nanoparticles (NPs) for use in therapeutic applications have largely not realized their clinical potential due to an overall inability to use in vitro results to predict NP performance in vivo. The avian embryo and associated chorioallantoic membrane (CAM) has eme...

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Detalles Bibliográficos
Autores principales: Butler, Kimberly S., Brinker, C. Jeffrey, Leong, Hon Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799072/
https://www.ncbi.nlm.nih.gov/pubmed/36453753
http://dx.doi.org/10.1021/acsnano.2c03990