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PHLPP1 deficiency protects against age‐related intervertebral disc degeneration
BACKGROUND: Intervertebral disc (IVD) degeneration is strongly associated with low back pain and is highly prevalent in the elderly population. Hallmarks of IVD degeneration include cell loss and extracellular matrix degradation. The PH domain leucine‐rich‐repeats protein phosphatase (PHLPP1) is hig...
Autores principales: | Zhang, Changli, Joseph, Katherine M., Khan, Nazir M., Diaz‐Hernandez, Martha Elena, Drissi, Hicham, Illien‐Junger, Svenja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799085/ https://www.ncbi.nlm.nih.gov/pubmed/36601379 http://dx.doi.org/10.1002/jsp2.1224 |
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