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Effects of N-methyl-D-aspartate receptor knockdown and hypoxia/reoxygenation injury on the neuronal proteome and transcriptome

INTRODUCTION: Brain tissue is extremely sensitive to hypoxia/reoxygenation (H/R) injury, which can easily cause irreversible damage to neurons. H/R injury can induce neuronal apoptosis through glutamate-mediated excitotoxicity. N-methyl-d-aspartate receptor (NMDAR) is one of the main receptors of ex...

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Detalles Bibliográficos
Autores principales: He, Jinting, Chen, Kaili, Sui, Yujie, Yang, Qiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799235/
https://www.ncbi.nlm.nih.gov/pubmed/36590918
http://dx.doi.org/10.3389/fnmol.2022.1004375