Elucidating the effect of iron acquisition systems in Klebsiella pneumoniae on susceptibility to the novel siderophore-cephalosporin cefiderocol

BACKGROUND: Cefiderocol (CFDC) is a novel siderophore-cephalosporin, effective against multidrug-resistant Gram-negative bacteria. As it has a siderophore side chain, it can utilize iron acquisition systems for penetration of the bacterial outer membrane. We aimed to elucidate the role of siderophor...

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Detalles Bibliográficos
Autores principales: Daoud, Lana, Al-Marzooq, Farah, Moubareck, Carole Ayoub, Ghazawi, Akela, Collyns, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799297/
https://www.ncbi.nlm.nih.gov/pubmed/36580460
http://dx.doi.org/10.1371/journal.pone.0277946

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799297/
https://www.ncbi.nlm.nih.gov/pubmed/36580460
http://dx.doi.org/10.1371/journal.pone.0277946

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