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Elucidating the effect of iron acquisition systems in Klebsiella pneumoniae on susceptibility to the novel siderophore-cephalosporin cefiderocol
BACKGROUND: Cefiderocol (CFDC) is a novel siderophore-cephalosporin, effective against multidrug-resistant Gram-negative bacteria. As it has a siderophore side chain, it can utilize iron acquisition systems for penetration of the bacterial outer membrane. We aimed to elucidate the role of siderophor...
Autores principales: | Daoud, Lana, Al-Marzooq, Farah, Moubareck, Carole Ayoub, Ghazawi, Akela, Collyns, Timothy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799297/ https://www.ncbi.nlm.nih.gov/pubmed/36580460 http://dx.doi.org/10.1371/journal.pone.0277946 |
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