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Systematic comparison of modeling fidelity levels and parameter inference settings applied to negative feedback gene regulation

Quantitative stochastic models of gene regulatory networks are important tools for studying cellular regulation. Such models can be formulated at many different levels of fidelity. A practical challenge is to determine what model fidelity to use in order to get accurate and representative results. T...

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Detalles Bibliográficos
Autores principales: Coulier, Adrien, Singh, Prashant, Sturrock, Marc, Hellander, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799300/
https://www.ncbi.nlm.nih.gov/pubmed/36520957
http://dx.doi.org/10.1371/journal.pcbi.1010683