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Systematic analysis of cilia characteristics and Hedgehog signaling in five immortal cell lines

Dysfunction of the primary cilium, a microtubule-based signaling organelle, leads to genetic conditions called ciliopathies. Hedgehog (Hh) signaling is mediated by the primary cilium in vertebrates and is therefore implicated in ciliopathies; however, it is not clear which immortal cell lines are th...

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Detalles Bibliográficos
Autores principales: Gómez, Arianna Ericka, Christman, Angela K., Van De Weghe, Julie Craft, Finn, Malaney, Doherty, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799305/
https://www.ncbi.nlm.nih.gov/pubmed/36580465
http://dx.doi.org/10.1371/journal.pone.0266433