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Systematic analysis of cilia characteristics and Hedgehog signaling in five immortal cell lines
Dysfunction of the primary cilium, a microtubule-based signaling organelle, leads to genetic conditions called ciliopathies. Hedgehog (Hh) signaling is mediated by the primary cilium in vertebrates and is therefore implicated in ciliopathies; however, it is not clear which immortal cell lines are th...
Autores principales: | Gómez, Arianna Ericka, Christman, Angela K., Van De Weghe, Julie Craft, Finn, Malaney, Doherty, Dan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799305/ https://www.ncbi.nlm.nih.gov/pubmed/36580465 http://dx.doi.org/10.1371/journal.pone.0266433 |
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