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Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish–A novel insight into its action mechanism

Growth differentiation factor 9 (GDF9) was the first oocyte-specific growth factor identified; however, most information about GDF9 functions comes from studies in the mouse model. In this study, we created a mutant for Gdf9 gene (gdf9-/-) in zebrafish using TALEN approach. The loss of Gdf9 caused a...

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Detalles Bibliográficos
Autores principales: Chen, Weiting, Zhai, Yue, Zhu, Bo, Wu, Kun, Fan, Yuqin, Zhou, Xianqing, Liu, Lin, Ge, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799306/
https://www.ncbi.nlm.nih.gov/pubmed/36520929
http://dx.doi.org/10.1371/journal.pgen.1010318