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Loss of growth differentiation factor 9 causes an arrest of early folliculogenesis in zebrafish–A novel insight into its action mechanism
Growth differentiation factor 9 (GDF9) was the first oocyte-specific growth factor identified; however, most information about GDF9 functions comes from studies in the mouse model. In this study, we created a mutant for Gdf9 gene (gdf9-/-) in zebrafish using TALEN approach. The loss of Gdf9 caused a...
Autores principales: | Chen, Weiting, Zhai, Yue, Zhu, Bo, Wu, Kun, Fan, Yuqin, Zhou, Xianqing, Liu, Lin, Ge, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799306/ https://www.ncbi.nlm.nih.gov/pubmed/36520929 http://dx.doi.org/10.1371/journal.pgen.1010318 |
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