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Investigating the potential impact of PCSK9-inhibitors on mood disorders using eQTL-based Mendelian randomization
Prescription of PCSK9-inhibitors has increased in recent years but not much is known about its off-target effects. PCSK9-expression is evident in non-hepatic tissues, notably the brain, and genetic variation in the PCSK9 locus has recently been shown to be associated with mood disorder-related trait...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799310/ https://www.ncbi.nlm.nih.gov/pubmed/36580462 http://dx.doi.org/10.1371/journal.pone.0279381 |