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Loss of Slc12a2 specifically in pancreatic β-cells drives metabolic syndrome in mice

The risk of type-2 diabetes and cardiovascular disease is higher in subjects with metabolic syndrome, a cluster of clinical conditions characterized by obesity, impaired glucose metabolism, hyperinsulinemia, hyperlipidemia and hypertension. Diuretics are frequently used to treat hypertension in thes...

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Detalles Bibliográficos
Autores principales: Abdelgawad, Rana, Rathod, Yakshkumar Dilipbhai, Alshammari, Modhi, Kelly, Lisa, Hübner, Christian A., Aguilar-Bryan, Lydia, Di Fulvio, Mauricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799326/
https://www.ncbi.nlm.nih.gov/pubmed/36580474
http://dx.doi.org/10.1371/journal.pone.0279560