Calcium signaling induced by 15-deoxy-prostamide-J(2) promotes cell death by activating PERK, IP3R, and the mitochondrial permeability transition pore

Melanoma is the deadliest form of skin cancer in the US. Although immunotherapeutic checkpoint inhibitors and small-molecule kinase inhibitors have dramatically increased the survival of patients with melanoma, new or optimized therapeutic approaches are still needed to improve outcomes. 15-deoxy-Δ(...

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Detalles Bibliográficos
Autores principales: Ladin, Daniel A., Nelson, Margaret M., Cota, Estefani, Colonna, Catherine, Burns, Colin, Robidoux, Jacques, Fisher-Wellman, Kelsey H., Van Dross-Anderson, Rukiyah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799328/
https://www.ncbi.nlm.nih.gov/pubmed/36580536
http://dx.doi.org/10.18632/oncotarget.28334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799328/
https://www.ncbi.nlm.nih.gov/pubmed/36580536
http://dx.doi.org/10.18632/oncotarget.28334

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