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Working strokes produced by curling protofilaments at disassembling microtubule tips can be biochemically tuned and vary with species

The disassembly of microtubules can generate force and drive intracellular motility. During mitosis, for example, chromosomes remain persistently attached via kinetochores to the tips of disassembling microtubules, which pull the sister chromatids apart. According to the conformational wave hypothes...

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Detalles Bibliográficos
Autores principales: Murray, Lucas E, Kim, Haein, Rice, Luke M, Asbury, Charles L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799970/
https://www.ncbi.nlm.nih.gov/pubmed/36580070
http://dx.doi.org/10.7554/eLife.83225