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Single amino acid residue mediates reciprocal specificity in two mosquito odorant receptors

The southern house mosquito, Culex quinquefasciatus, utilizes two odorant receptors, CquiOR10 and CquiOR2, narrowly tuned to oviposition attractants and well conserved among mosquito species. They detect skatole and indole, respectively, with reciprocal specificity. We swapped the transmembrane (TM)...

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Detalles Bibliográficos
Autores principales: Franco, Flavia P, Xu, Pingxi, Harris, Brandon J, Yarov-Yarovoy, Vladimir, Leal, Walter S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9799979/
https://www.ncbi.nlm.nih.gov/pubmed/36511779
http://dx.doi.org/10.7554/eLife.82922