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Identification of a small molecule 0390 as a potent antimicrobial agent to combat antibiotic-resistant Escherichia coli

INTRODUCTION: Antibiotic resistance has posed a serious challenge to global public health. With the increasing resistance emergence of E. coli and mortality caused by drug-resistant E. coli infections, it is urgent to develop novel antibiotics. METHODS: By high-throughput screening assay, we found a...

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Detalles Bibliográficos
Autores principales: Li, Linhui, She, Pengfei, Liu, Shasha, Li, Yimin, Li, Zehao, Yang, Yifan, Zhou, Linying, Wu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800007/
https://www.ncbi.nlm.nih.gov/pubmed/36590392
http://dx.doi.org/10.3389/fmicb.2022.1078318