Survival-based CRISPR genetic screens across a panel of permissive cell lines identify common and cell-specific SARS-CoV-2 host factors

SARS-CoV-2 depends on host cell components for infection and replication. Identification of virus-host dependencies offers an effective way to elucidate mechanisms involved in viral infection and replication. If druggable, host factor dependencies may present an attractive strategy for anti-viral th...

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Detalles Bibliográficos
Autores principales: Chan, Katherine, Farias, Adrian Granda, Lee, Hunsang, Guvenc, Furkan, Mero, Patricia, Brown, Kevin R., Ward, Henry, Billmann, Maximilian, Aulakh, Kamaldeep, Astori, Audrey, Haider, Shahan, Marcon, Edyta, Braunschweig, Ulrich, Pu, Shuye, Habsid, Andrea, Yan Tong, Amy Hin, Christie-Holmes, Natasha, Budylowski, Patrick, Ghalami, Ayoob, Mubareka, Samira, Maguire, Finlay, Banerjee, Arinjay, Mossman, Karen L., Greenblatt, Jack, Gray-Owen, Scott D., Raught, Brian, Blencowe, Benjamin J., Taipale, Mikko, Myers, Chad, Moffat, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800021/
https://www.ncbi.nlm.nih.gov/pubmed/36597481
http://dx.doi.org/10.1016/j.heliyon.2022.e12744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800021/
https://www.ncbi.nlm.nih.gov/pubmed/36597481
http://dx.doi.org/10.1016/j.heliyon.2022.e12744

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