Transcriptional inhibition of STAT1 functions in the nucleus alleviates Th1 and Th17 cell-mediated inflammatory diseases

T helper 1 cells (Th1 cells) and T helper 17 cells (Th17 cells) play pivotal roles in the pathogenesis of various autoimmune diseases, including psoriasis and inflammatory bowel disease (IBD). Signal transducer and activator of transcription 1 (STAT1) regulates the Th1 and Th17 cell lineage commitme...

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Detalles Bibliográficos
Autores principales: Park, Jiyoon, Son, Min-Ji, Ho, Chun-Chang, Lee, Su-Hyeon, Kim, Yuna, An, Jaekyeung, Lee, Sang-Kyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800178/
https://www.ncbi.nlm.nih.gov/pubmed/36591260
http://dx.doi.org/10.3389/fimmu.2022.1054472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800178/
https://www.ncbi.nlm.nih.gov/pubmed/36591260
http://dx.doi.org/10.3389/fimmu.2022.1054472

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