Cargando…
Transcriptional inhibition of STAT1 functions in the nucleus alleviates Th1 and Th17 cell-mediated inflammatory diseases
T helper 1 cells (Th1 cells) and T helper 17 cells (Th17 cells) play pivotal roles in the pathogenesis of various autoimmune diseases, including psoriasis and inflammatory bowel disease (IBD). Signal transducer and activator of transcription 1 (STAT1) regulates the Th1 and Th17 cell lineage commitme...
Autores principales: | Park, Jiyoon, Son, Min-Ji, Ho, Chun-Chang, Lee, Su-Hyeon, Kim, Yuna, An, Jaekyeung, Lee, Sang-Kyou |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800178/ https://www.ncbi.nlm.nih.gov/pubmed/36591260 http://dx.doi.org/10.3389/fimmu.2022.1054472 |
Ejemplares similares
-
Corrigendum: Transcriptional inhibition of STAT1 functions in the nucleus alleviates Th1 and Th17 cell-mediated inflammatory diseases
por: Park, Jiyoon, et al.
Publicado: (2023) -
Intranuclear Delivery of HIF-1α-TMD Alleviates EAE via Functional Conversion of TH17 Cells
por: Shin, Jin-Su, et al.
Publicado: (2021) -
The transcription factor ELF4 alleviates inflammatory bowel disease by activating IL1RN transcription, suppressing inflammatory TH17 cell activity, and inducing macrophage M2 polarization
por: Cao, Meiwan, et al.
Publicado: (2023) -
Increased Development of Th1, Th17, and Th1.17 Cells Under T1 Polarizing Conditions in Juvenile Idiopathic Arthritis
por: Patrick, Anna E., et al.
Publicado: (2022) -
The Multifaceted Role of Th1, Th9, and Th17 Cells in Immune Checkpoint Inhibition Therapy
por: Lee, Jongdae, et al.
Publicado: (2021)