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In vitro and in silico study of an exclusive insertion in the nicotinamide/nicotinate mononucleotide adenylyltransferase from Leishmania braziliensis

The intracellular parasite Leishmania braziliensis is the causal agent of cutaneous and mucocutaneous leishmaniasis, a group of endemic diseases in tropical regions, including Latin America. New therapeutic targets are required to inhibit the pathogen without affecting the host. The enzyme nicotinam...

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Detalles Bibliográficos
Autores principales: Ortiz-Joya, Lesly Johanna, Contreras Rodríguez, Luis Ernesto, Ochoa, Rodrigo, Ramírez Hernández, María Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800193/
https://www.ncbi.nlm.nih.gov/pubmed/36590501
http://dx.doi.org/10.1016/j.heliyon.2022.e12203