Post-irradiation intratumoral heterogeneity modulates response to immune checkpoint inhibition therapy in a murine melanoma model

PURPOSE: The underlying mechanism for radiation as a potentiator of immune checkpoint inhibition (ICI) is unclear. We developed a novel murine model to investigate the effects of post-irradiation intratumoral heterogeneity (ITH) on response to ICI. EXPERIMENTAL DESIGN: Parental mouse melanoma B16F10...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Sud, Shivani, Qu, Yanli, Li, Liantao, Zhang, Jiajie, Marron, David, Knape, Nicole Michelle, Kim, Isaiah James, Wagner, Kyle Thomas, Zhang, Tian, Zhao, Yuxia, Guo, Genyan, Wang, Andrew Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Radiation and Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800194/
https://www.ncbi.nlm.nih.gov/pubmed/36571944
http://dx.doi.org/10.1016/j.neo.2022.100864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800194/
https://www.ncbi.nlm.nih.gov/pubmed/36571944
http://dx.doi.org/10.1016/j.neo.2022.100864

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