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Itaconate promotes a wound resolving phenotype in pro-inflammatory macrophages

Pathological conditions associated with dysfunctional wound healing are characterized by impaired remodelling of extracellular matrix (ECM), increased macrophage infiltration, and chronic inflammation. Macrophages also play an important role in wound healing as they drive wound closure by secretion...

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Detalles Bibliográficos
Autores principales: Maassen, Sjors, Coenen, Britt, Ioannidis, Melina, Harber, Karl, Grijpstra, Pieter, Van den Bossche, Jan, van den Bogaart, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800195/
https://www.ncbi.nlm.nih.gov/pubmed/36574745
http://dx.doi.org/10.1016/j.redox.2022.102591