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Itaconate promotes a wound resolving phenotype in pro-inflammatory macrophages
Pathological conditions associated with dysfunctional wound healing are characterized by impaired remodelling of extracellular matrix (ECM), increased macrophage infiltration, and chronic inflammation. Macrophages also play an important role in wound healing as they drive wound closure by secretion...
Autores principales: | Maassen, Sjors, Coenen, Britt, Ioannidis, Melina, Harber, Karl, Grijpstra, Pieter, Van den Bossche, Jan, van den Bogaart, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800195/ https://www.ncbi.nlm.nih.gov/pubmed/36574745 http://dx.doi.org/10.1016/j.redox.2022.102591 |
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