AM-879, a PPARy non-agonist and Ser273 phosphorylation blocker, promotes insulin sensitivity without adverse effects in mice

Obesity is one of the main risk factors for type 2 diabetes, and peroxisome proliferator-activated receptor γ (PPARγ) is considered a promising pathway on insulin sensitivity and adipose tissue metabolism. The search for molecules acting as insulin sensitizers have increased, especially for molecule...

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Detalles Bibliográficos
Autores principales: Terra, M.F., García-Arévalo, M., Avelino, T.M., Degaki, K.Y., Malospirito, C.C., de Carvalho, M., Torres, F.R., Saito, Â., Figueira, A.C.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800205/
https://www.ncbi.nlm.nih.gov/pubmed/36588655
http://dx.doi.org/10.1016/j.metop.2022.100221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800205/
https://www.ncbi.nlm.nih.gov/pubmed/36588655
http://dx.doi.org/10.1016/j.metop.2022.100221

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