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Functional divergence of the sarcomeric myosin, MYH7b, supports species-specific biological roles

Myosin heavy chain 7b (MYH7b) is an evolutionarily ancient member of the sarcomeric myosin family, which typically supports striated muscle function. However, in mammals, alternative splicing prevents MYH7b protein production in cardiac and most skeletal muscles and limits expression to a subset of...

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Detalles Bibliográficos
Autores principales: Lee, Lindsey A., Barrick, Samantha K., Meller, Artur, Walklate, Jonathan, Lotthammer, Jeffrey M., Tay, Jian Wei, Stump, W. Tom, Bowman, Gregory, Geeves, Michael A., Greenberg, Michael J., Leinwand, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800208/
https://www.ncbi.nlm.nih.gov/pubmed/36334627
http://dx.doi.org/10.1016/j.jbc.2022.102657