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阻断PAK1激酶活性对急性巨核细胞白血病细胞分化及凋亡的影响

OBJECTIVE: To investigate the effect of blocking P21 activated kinase 1 (PAK1) activity on the proliferation, differentiation, and apoptosis of acute megakaryocytic leukemia (AMKL) cell lines (CHRF and CMK). METHODS: Cell counts were used to detect the effects of PAK1 inhibitors (IPA-3 and G5555) on...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800214/
https://www.ncbi.nlm.nih.gov/pubmed/35968594
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.06.010