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CD19嵌合抗原受体T细胞制备条件优化及其体内外杀伤作用研究

OBJECTIVE: To optimize the stimulation and activation system of mouse CD3(+) T cells in vitro and explore the optimal infection time of CD3(+) T cells to establish mouse CD19 chimeric antigen receptor T cells (mCD19 CAR-T), and to also verify its killing effect in vivo and in vitro. METHODS: Splenic...

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Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial office of Chinese Journal of Hematology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800219/
https://www.ncbi.nlm.nih.gov/pubmed/35968595
http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2022.06.011