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Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C(6) unit for terpenoid biosynthesis

Terpenoids constitute the largest class of natural products with complex structures, essential functions, and versatile applications. Creation of new building blocks beyond the conventional five-carbon (C(5)) units, dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate, expands significantly...

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Detalles Bibliográficos
Autores principales: Xia, Chen-Yang, Lu, Bo-Wen, Cui, Ji-Yun, Wang, Bai-Yang, Sun, Yue-Yang, Gan, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800250/
https://www.ncbi.nlm.nih.gov/pubmed/36605705
http://dx.doi.org/10.1016/j.synbio.2022.12.002