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Engineered geranyl diphosphate methyltransferase produces 2-methyl-dimethylallyl diphosphate as a noncanonical C(6) unit for terpenoid biosynthesis
Terpenoids constitute the largest class of natural products with complex structures, essential functions, and versatile applications. Creation of new building blocks beyond the conventional five-carbon (C(5)) units, dimethylallyl diphosphate (DMAPP) and isopentenyl diphosphate, expands significantly...
Autores principales: | Xia, Chen-Yang, Lu, Bo-Wen, Cui, Ji-Yun, Wang, Bai-Yang, Sun, Yue-Yang, Gan, Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800250/ https://www.ncbi.nlm.nih.gov/pubmed/36605705 http://dx.doi.org/10.1016/j.synbio.2022.12.002 |
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