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Differential roles of Aβ42/40, p-tau231 and p-tau217 for Alzheimer’s trial selection and disease monitoring

Blood biomarkers indicative of Alzheimer’s disease (AD) pathology are altered in both preclinical and symptomatic stages of the disease. Distinctive biomarkers may be optimal for the identification of AD pathology or monitoring of disease progression. Blood biomarkers that correlate with changes in...

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Detalles Bibliográficos
Autores principales: Ashton, Nicholas J., Janelidze, Shorena, Mattsson-Carlgren, Niklas, Binette, Alexa Pichet, Strandberg, Olof, Brum, Wagner S., Karikari, Thomas K., González-Ortiz, Fernándo, Di Molfetta, Guglielmo, Meda, Francisco J., Jonaitis, Erin M., Koscik, Rebecca Langhough, Cody, Karly, Betthauser, Tobey J., Li, Yan, Vanmechelen, Eugeen, Palmqvist, Sebastian, Stomrud, Erik, Bateman, Randall J., Zetterberg, Henrik, Johnson, Sterling C., Blennow, Kaj, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800279/
https://www.ncbi.nlm.nih.gov/pubmed/36456833
http://dx.doi.org/10.1038/s41591-022-02074-w