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Alternative normalization and analysis pipeline to address systematic bias in NanoString GeoMx Digital Spatial Profiling data

Spatial transcriptomics is a novel technique that provides RNA-expression data with tissue-contextual annotations. Quality assessments of such techniques using end-user generated data are often lacking. Here, we evaluated data from the NanoString GeoMx Digital Spatial Profiling (DSP) platform and st...

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Detalles Bibliográficos
Autores principales: van Hijfte, Levi, Geurts, Marjolein, Vallentgoed, Wies R., Eilers, Paul H.C., Sillevis Smitt, Peter A.E., Debets, Reno, French, Pim J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800292/
https://www.ncbi.nlm.nih.gov/pubmed/36590163
http://dx.doi.org/10.1016/j.isci.2022.105760