S-acylation of Sprouty and SPRED proteins by the S-acyltransferase zDHHC17 involves a novel mode of enzyme–substrate interaction

S-acylation is an essential post-translational modification, which is mediated by a family of 23 zDHHC enzymes in humans. Several thousand proteins are modified by S-acylation; however, we lack a detailed understanding of how enzyme–substrate recognition and specificity is achieved. Previous work sh...

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Detalles Bibliográficos
Autores principales: Butler, Liam, Locatelli, Carolina, Allagioti, Despoina, Lousa, Irina, Lemonidis, Kimon, Tomkinson, Nicholas C.O., Salaun, Christine, Chamberlain, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800311/
https://www.ncbi.nlm.nih.gov/pubmed/36442513
http://dx.doi.org/10.1016/j.jbc.2022.102754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800311/
https://www.ncbi.nlm.nih.gov/pubmed/36442513
http://dx.doi.org/10.1016/j.jbc.2022.102754

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