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Paeoniflorin alleviates inflammatory response in IBS-D mouse model via downregulation of the NLRP3 inflammasome pathway with involvement of miR-29a

Paeoniflorin has been traditionally used to treat pain and immunologic derangement in China. However, its detailed mechanism remains to be illuminated. We investigated the mechanism by which paeoniflorin alleviates the inflammatory response in a mouse model of irritable bowel syndrome with predomina...

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Detalles Bibliográficos
Autores principales: Ke, Wei, Wang, Yongfu, Huang, Siyu, Liu, Shan, Zhu, He, Xie, Xiangyu, Yang, Huifei, Lu, Qin, Gan, Jianfeng, He, Guodong, Che, Fei, Wan, Xin, Tang, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800317/
https://www.ncbi.nlm.nih.gov/pubmed/36590561
http://dx.doi.org/10.1016/j.heliyon.2022.e12312