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Determinants of receptor tyrosine phosphatase homophilic adhesion: Structural comparison of PTPRK and PTPRM extracellular domains

Type IIB receptor protein tyrosine phosphatases are cell surface transmembrane proteins that engage in cell adhesion via their extracellular domains (ECDs) and cell signaling via their cytoplasmic phosphatase domains. The ECDs of type IIB receptor protein tyrosine phosphatases form stable, homophili...

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Detalles Bibliográficos
Autores principales: Hay, Iain M., Shamin, Maria, Caroe, Eve R., Mohammed, Ahmed S.A., Svergun, Dmitri I., Jeffries, Cy M., Graham, Stephen C., Sharpe, Hayley J., Deane, Janet E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800333/
https://www.ncbi.nlm.nih.gov/pubmed/36436563
http://dx.doi.org/10.1016/j.jbc.2022.102750