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Exploration of the cysteine reactivity of human inducible Hsp70 and cognate Hsc70

Hsp70s are multifunctional proteins and serve as the central hub of the protein quality control network. Hsp70s are also related to a number of diseases and have been established as drug targets. Human HspA1A (hHsp70) and HspA8 (hHsc70) are the major cytosolic Hsp70s, and they have both overlapping...

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Detalles Bibliográficos
Autores principales: Hong, Zhouping, Gong, Weibin, Yang, Jie, Li, Sainan, Liu, Zhenyan, Perrett, Sarah, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800336/
https://www.ncbi.nlm.nih.gov/pubmed/36410435
http://dx.doi.org/10.1016/j.jbc.2022.102723