Studies of the symmetric binding mode of daclatasvir and analogs using a new homology model of HCV NS5A GT-4a
CONTEXT: Egypt has a high prevalence of the hepatitis C virus (HCV) genotype 4a (GT-4a). Unfortunately, the high resistance it exhibited still was not given the deserved attention in the scientific community. There is currently no consensus on the NS5A binding site because the crystal structure of H...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800351/ https://www.ncbi.nlm.nih.gov/pubmed/36580076 http://dx.doi.org/10.1007/s00894-022-05420-4 |