Studies of the symmetric binding mode of daclatasvir and analogs using a new homology model of HCV NS5A GT-4a

CONTEXT: Egypt has a high prevalence of the hepatitis C virus (HCV) genotype 4a (GT-4a). Unfortunately, the high resistance it exhibited still was not given the deserved attention in the scientific community. There is currently no consensus on the NS5A binding site because the crystal structure of H...

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Detalles Bibliográficos
Autores principales: Saad, Kholoud A., Eldawy, Mohammed A., Elokely, Khaled M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800351/
https://www.ncbi.nlm.nih.gov/pubmed/36580076
http://dx.doi.org/10.1007/s00894-022-05420-4