An intranasal recombinant NDV-BRSV F(opt) vaccine is safe and reduces lesion severity in a colostrum-deprived calf model of RSV infection

Human respiratory syncytial virus (HRSV) is a major cause of severe lower respiratory tract disease in infants and the elderly, yet no safe, effective vaccine is commercially available. Closely related bovine RSV (BRSV) causes respiratory disease in young calves, with many similar features to those...

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Detalles Bibliográficos
Autores principales: Sacco, Randy E., Mena, Ignacio, Palmer, Mitchell V., Durbin, Russell K., García-Sastre, Adolfo, Durbin, Joan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800378/
https://www.ncbi.nlm.nih.gov/pubmed/36581658
http://dx.doi.org/10.1038/s41598-022-26938-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800378/
https://www.ncbi.nlm.nih.gov/pubmed/36581658
http://dx.doi.org/10.1038/s41598-022-26938-w

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