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Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice

One goal of regenerative medicine is to rejuvenate tissues and extend lifespan by restoring the function of endogenous aged stem cells. However, evidence that somatic stem cells can be targeted in vivo to extend lifespan is still lacking. Here, we demonstrate that after a short systemic treatment wi...

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Detalles Bibliográficos
Autores principales: Montserrat-Vazquez, Sara, Ali, Noelle J., Matteini, Francesca, Lozano, Javier, Zhaowei, Tu, Mejia-Ramirez, Eva, Marka, Gina, Vollmer, Angelika, Soller, Karin, Sacma, Mehmet, Sakk, Vadim, Mularoni, Loris, Mallm, Jan Philipp, Plass, Mireya, Zheng, Yi, Geiger, Hartmut, Florian, M. Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800381/
https://www.ncbi.nlm.nih.gov/pubmed/36581635
http://dx.doi.org/10.1038/s41536-022-00275-y