p53 regulates lysosomal membrane permeabilization as well as cytoprotective autophagy in response to DNA-damaging drugs

Lysosomes are single-membraned organelles that mediate the intracellular degradation of macromolecules. Various stress can induce lysosomal membrane permeabilization (LMP), translocating intralysosomal components, such as cathepsins, to the cytoplasm, which induces lysosomal-dependent cell death (LD...

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Detalles Bibliográficos
Autores principales: Yamashita, Gai, Takano, Naoharu, Kazama, Hiromi, Tsukahara, Kiyoaki, Miyazawa, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800408/
https://www.ncbi.nlm.nih.gov/pubmed/36581628
http://dx.doi.org/10.1038/s41420-022-01293-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800408/
https://www.ncbi.nlm.nih.gov/pubmed/36581628
http://dx.doi.org/10.1038/s41420-022-01293-x

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