TAPE-seq is a cell-based method for predicting genome-wide off-target effects of prime editor

Prime editors (PEs) are powerful tools that widen the possibilities for sequence modifications during genome editing. Although methods based on the analysis of Cas9 nuclease or nickase activity have been used to predict genome-wide off-target activities of PEs, no tool that directly uses PEs for thi...

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Detalles Bibliográficos
Autores principales: Kwon, Jeonghun, Kim, Minyoung, Bae, Seungmin, Jo, Anna, Kim, Youngho, Lee, Jungjoon K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800413/
https://www.ncbi.nlm.nih.gov/pubmed/36581624
http://dx.doi.org/10.1038/s41467-022-35743-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800413/
https://www.ncbi.nlm.nih.gov/pubmed/36581624
http://dx.doi.org/10.1038/s41467-022-35743-y

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