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Investigating the causal mediating effect of type 2 diabetes on the relationship between traits and systolic blood pressure: A two-step Mendelian randomization study

BACKGROUND: Type 2 diabetes mellitus (T2DM) and hypertension commonly coexist, and we presumed that T2DM might mediate the relationship between some shared risk factors and systolic blood pressure (SBP). METHODS: The causal association between T2DM and SBP was first confirmed using Mendelian randomi...

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Detalles Bibliográficos
Autores principales: Hao, Xuezeng, Li, Weixin, Shi, Ruiqing, Wang, Qiuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800519/
https://www.ncbi.nlm.nih.gov/pubmed/36589843
http://dx.doi.org/10.3389/fendo.2022.1090867