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Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice

Mucus forms the first line of defence of the intestinal mucosa barrier, and mucin is its core component. Glutamine is a vital energy substance for goblet cells; it can promote mucus synthesis and alleviate damage to the intestinal mucus barrier after burn injury, but its mechanism is not fully under...

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Detalles Bibliográficos
Autores principales: Wu, Dan, Su, Sen, Zha, Xule, Wei, Yan, Yang, Gang, Huang, Qianying, Yang, Yongjun, Xia, Lin, Fan, Shijun, Peng, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800542/
https://www.ncbi.nlm.nih.gov/pubmed/36565645
http://dx.doi.org/10.1016/j.redox.2022.102581